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Drosophila larval neuromuscular junction
Contact info:
Email: arodal@brandeis.edu
Office: 781-736-2459
Lab: 781-736-4954
Fax: 781-736-2405
Lab location:
Rosenstiel Basic Medical
Sciences Research Center
Room 527
Mailing address:
The Rodal Lab - MS029
415 South Street
Waltham, MA 02454
Welcome to the Rodal Lab
Cells self-organize by continuously remodeling internal membrane compartments that move and sort signaling, structural, and metabolic cargo. Our goal is to understand how specialized cells like neurons deploy membrane-remodeling machinery to build and regulate these highly dynamic membrane structures. Using the fruit fly Drosophila as a primary model, we combine in vivo imaging of membrane traffic, mechanistic biochemistry, phenotypic analysis of mutants lacking this machinery, and evidence from disease models to approach these cell biological questions from multiple angles.